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dikicilab

brings together young and motivated researchers with a shared passion for advancing the fields of biomaterials and tissue engineering. 

Research Projects

✦ Bilayer Skin Substitute with Bioactive and Antimicrobial Features

The Scientific and Technological Research Council of Turkey (TUBITAK) - 3501 Career Development Grant, Grant No. 221S594

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✦ Decellularized Plant-Based Biomaterials for Management of Chronic Wounds

Izmir Institute of Technology Research Foundation (IZTECH BAP), Grant No. 2021IYTE‑1‑0057

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✦ Three-dimensional (3D) biomimetic human gut model from decellularized plants

Research Universities Support Program (ADEP) - Council of Higher Education (CoHE), Grant No. 2022IYTE‑3‑0002

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✦ Tissue-engineered vascular grafts (TEVG) from decellularized parsley stems

Health Institutes of Türkiye (TÜSEB), Grant No. 2023-A4-01-31747

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✦ Pro-angiogenic wound dressings from decellularized spinach leaves

Health Institutes of Türkiye (TÜSEB), Grant No. 2023-A4-01-31614

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✦ Tissue-engineered vascular grafts (TEVGs) from polymeric bioamterials 

Health Institutes of Türkiye (TÜSEB), Grant No. 2023-A4-01-31942

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✦ 2-deoxy-D-ribose (2dDR) loaded pro-angiogenic synthetic wound dressings

Health Institutes of Türkiye (TÜSEB), Grant No. 2023-A4-01-31967

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Our group is dedicated to the design and development of innovative biomaterials and tissue-engineered constructs that address pressing clinical challenges and improve patient outcomes. While our main focus lies in biomaterials, tissue engineering, and angiogenesis, our research scope extends across related fields at the intersection of material science, bioengineering, and biology. 

 

Through this interdisciplinary approach, we strive to develop biomimetic solutions that accelerate healing, promote vascularization and functional tissue integration, and provide reliable, next-generation alternatives to current clinical practices.

Pro-Angiogenic Biomaterials

Designing novel biomaterials to promote angiogenesis, accelerate tissue repair, and enable timely vascularization of tissue-engineered constructs.

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Vascular Tissue Engineering

Developing biodegradable, biomimetic tissue-engineered vascular grafts (TEVGs) for small-diameter vessels and comprehensively assessing their structural, functional, and biological performance.

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Wound Healing and Skin Substitutes
Creating polymer-based materials and skin substitute systems for chronic wound management.

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3D In Vitro Tissue and Disease Models

Developing advanced 3D tissue and disease models to study drug responses and mechanical dynamics in line with the 3R principles.
 

CAM Assay and Alternative In Vivo Models
Utilizing the ex ovo chick chorioallantoic membrane (CAM) assay as an ethical, rapid, and cost-effective in vivo model to investigate angiogenesis and biomaterial–tissue interactions.

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